Description

5-Bromo-2-Chloro-4-Hydroxybenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique substitution pattern makes it a valuable scaffold for constructing complex molecules, particularly in medicinal chemistry and agrochemical research. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Organic Synthesis Building Block: A versatile precursor for constructing complex heterocycles and functionalized aromatic compounds via cross-coupling and nucleophilic substitution reactions.
• Material Science Research: Potential monomer or functional additive in the development of specialty polymers and advanced organic materials.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	5-Bromo-2-Chloro-4-Hydroxybenzonitrile
CAS No.	1259020-46-6
Molecular Formula	C7H3BrClNO
Molecular Weight	232.46 g/mol
Synonyms	4-Hydroxy-5-bromo-2-chlorobenzonitrile; 2-Chloro-5-bromo-4-hydroxybenzonitrile; 5-Bromo-2-chloro-4-hydroxybenzonitrile; Benzonitrile, 5-bromo-2-chloro-4-hydroxy-; 1259020-46-6
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Chloro-4-Hydroxybenzonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.