Description

Ethyl 2,3-Diamino-6-Fluorobenzoate is a high-purity fluorinated benzoate derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of amino and fluorine functional groups, which are essential for modulating the biological activity and physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated quinazoline, benzimidazole, and other nitrogen-containing heterocycles with potential therapeutic applications.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides where the fluorine atom enhances bioavailability and environmental stability.
• Material Science Precursor: Employed in the creation of specialized polymers, liquid crystals, and organic electronic materials requiring fluorinated aromatic amines.
• Chemical Biology Probes: Serves as a starting material for fluorescent tags and molecular probes used in diagnostic assays and cellular imaging.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects under cGMP conditions.

Basic Information

Product Name	Ethyl 2,3-Diamino-6-Fluorobenzoate
CAS No.	1258070-71-1
Molecular Formula	C9H11FN2O2
Molecular Weight	198.20 g/mol
Synonyms	Ethyl 6-Fluoro-2,3-diaminobenzoate; 2,3-Diamino-6-fluorobenzoic Acid Ethyl Ester; Benzoic acid, 2,3-diamino-6-fluoro-, ethyl ester; 6-Fluoro-2,3-diaminobenzoic Acid Ethyl Ester; Ethyl 2-amino-3-amino-6-fluorobenzoate; Ethyl 2,3-bis(amino)-6-fluorobenzoate; 1258070-71-1; EA 6523473
EINECS	Contact for details

Quality Control

Every batch of Ethyl 2,3-Diamino-6-Fluorobenzoate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our standard grade typically conforms to >97% purity (by HPLC), with custom purities (e.g., >98%, >99%) available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.