Description

(S)-4-Boc-3-Cyanomorpholine is a high-purity chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and other fine chemicals where stereochemical integrity is paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
• API Synthesis: Used in the construction of complex molecular scaffolds for Active Pharmaceutical Ingredients (APIs), leveraging its protected amine and nitrile functionalities.
• Asymmetric Synthesis: Serves as a precursor for catalysts or ligands in asymmetric synthesis due to its defined stereochemistry at the morpholine ring.
• Agrochemical Research: Employed in the development of new pesticides and herbicides where specific stereoisomers are required for optimal activity.
• Peptidomimetics: Useful in the design and synthesis of peptidomimetic compounds, where the morpholine core can mimic peptide bonds or introduce conformational constraints.
• Chemical Biology Probes: Acts as a building block for creating molecular probes used in biochemical and cellular studies to investigate biological pathways.

Basic Information

Product Name	(S)-4-Boc-3-Cyanomorpholine
CAS No.	1257856-86-2
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	(S)-tert-Butyl 3-cyano-4-morpholinecarboxylate; (S)-3-Cyano-4-morpholinecarboxylic acid tert-butyl ester; (S)-4-(tert-Butoxycarbonyl)-3-cyanomorpholine; (3S)-4-[(2-Methylpropan-2-yl)oxycarbonyl]-3-cyanomorpholine; (S)-Boc-3-cyanomorpholine; (S)-N-Boc-3-cyanomorpholine; (S)-4-Boc-3-cyano-morpholine
EINECS	Contact for details

Quality Control

Our (S)-4-Boc-3-Cyanomorpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.