Description

1H-Pyrrole-2,5-Dione, 1-(3-Aminopropyl)-, Hydrochloride is a functionalized maleimide derivative, a versatile building block prized for its dual reactivity from the amine and maleimide groups. This compound is critical for researchers and manufacturers requiring precise, high-purity intermediates for advanced synthesis. It is primarily utilized in the development of pharmaceuticals, bioconjugation reagents, and specialty polymers where controlled covalent bonding is essential.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in targeted drug delivery systems.
• Bioconjugation & Protein Labeling: Used to create stable thiol-reactive crosslinkers and probes for modifying antibodies, peptides, and other biomolecules.
• Polymer & Material Science: Serves as a functional monomer or crosslinking agent in the synthesis of smart polymers, hydrogels, and coatings.
• Chemical Biology Research: Employed in activity-based protein profiling (ABPP) and the study of enzyme inhibition mechanisms.
• Diagnostic Reagent Synthesis: A precursor for fluorescent dyes and other signaling molecules used in assay development.
• Agrochemical Research: Intermediate in the synthesis of novel compounds with potential biological activity.

Basic Information

Product Name	1H-Pyrrole-2,5-Dione, 1-(3-Aminopropyl)-, Hydrochloride
CAS No.	1257852-74-6
Molecular Formula	C7H11ClN2O2
Molecular Weight	190.63 g/mol
Synonyms	N-(3-Aminopropyl)maleimide hydrochloride; 1-(3-Aminopropyl)maleimide hydrochloride; 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)propan-1-amine hydrochloride; Maleimide-PEG3-amine hydrochloride; APMA hydrochloride; N1-(3-Aminopropyl)maleimide HCl; 1H-Pyrrole-2,5-dione, 1-(3-aminopropyl)-, monohydrochloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrrole-2,5-Dione, 1-(3-Aminopropyl)-, Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.