Description

Azetidin-1-Yl(Azetidin-3-Yl)Methanone is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique azetidine-based scaffold, which serves as a critical precursor in the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of protease inhibitors, kinase inhibitors, and other targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting enzymatic pathways.
• Medicinal Chemistry: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve the metabolic stability and potency of lead compounds.
• Protease Inhibitor Synthesis: Serves as a core building block for the construction of molecules designed to inhibit specific proteases involved in various disease states.
• Kinase Inhibitor Development: Employed in the synthesis of potential kinase inhibitors for oncology and inflammatory disease research.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex molecules at various scales.

Basic Information

Product Name	Azetidin-1-Yl(Azetidin-3-Yl)Methanone
CAS No.	1257293-97-2
Molecular Formula	C7H12N2O
Molecular Weight	140.18 g/mol
Synonyms	1-(Azetidin-3-ylcarbonyl)azetidine; 3-(Azetidine-1-carbonyl)azetidine; Azetidin-1-yl(azetidin-3-yl)methanone; 1-(Azetidine-3-carbonyl)azetidine; Azetidine-1,3-dicarboximide (cyclic form reference); 3-(1-Azetidinylcarbonyl)azetidine; N-(Azetidin-3-yl)azetidine-1-carboxamide
EINECS	Contact for details

Quality Control

Our Azetidin-1-Yl(Azetidin-3-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and non-GMP research environments, ensuring reliable and reproducible results for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.