Description

Propanamide, n-(2-Fluorophenyl)-2-Hydroxy-n-Methyl- CAS NO 1257227-64-7 is a specialized fluorinated amide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorophenyl group and a hydroxy-methyl amide moiety, makes it a valuable intermediate for constructing complex pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical development companies engaged in the discovery of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers with unique surface properties.
• Chemical Synthesis: Employed in academic and industrial laboratories for methodological studies and the preparation of complex fluorinated organic compounds.
• Ligand & Catalyst Development: Acts as a scaffold for designing novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Propanamide, n-(2-Fluorophenyl)-2-Hydroxy-n-Methyl- CAS NO 1257227-64-7
CAS No.	1257227-64-7
Molecular Formula	C10H12FNO2
Molecular Weight	197.21 g/mol
Synonyms	N-(2-Fluorophenyl)-2-hydroxy-N-methylpropanamide; 2-Hydroxy-N-methyl-N-(2-fluorophenyl)propanamide; α-Hydroxy-N-methyl-N-(o-fluorophenyl)propionamide; N-Methyl-N-(2-fluorophenyl)-2-hydroxypropanamide; Propanamide, 2-hydroxy-N-methyl-N-(2-fluorophenyl)-; o-Fluoro-N-methyl-N-(2-hydroxypropionyl)aniline; (RS)-N-(2-Fluorophenyl)-2-hydroxy-N-methylpropanamide
EINECS	Contact for details

Quality Control

Our Propanamide, n-(2-Fluorophenyl)-2-Hydroxy-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.