Description

n-(4-Chloro-3-Nitrophenyl)-4-(Trifluoromethyl)Benzothioamide is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzothioamide core functionalized with chloro, nitro, and trifluoromethyl groups. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research targeting kinase inhibitors and other small-molecule therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of potential drug candidates, especially for oncology and inflammatory diseases.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or precursor in the synthesis of compounds designed to modulate kinase activity.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated and fluorinated structure.
• Chemical Biology Probes: Utilized in academic and industrial research to create molecular probes for studying biological pathways and target validation.
• Material Science Precursor: Acts as a specialty monomer or additive in the development of advanced polymers and functional materials.

Basic Information

Product Name	n-(4-Chloro-3-Nitrophenyl)-4-(Trifluoromethyl)Benzothioamide
CAS No.	1257095-61-6
Molecular Formula	C14H8ClF3N2O2S
Molecular Weight	360.74 g/mol
Synonyms	4-Chloro-3-nitro-N-[4-(trifluoromethyl)phenyl]benzothioamide; N-(4-Chloro-3-nitrophenyl)-4-(trifluoromethyl)benzenecarbothioamide; 1257095-61-6; Benzothioamide, N-(4-chloro-3-nitrophenyl)-4-(trifluoromethyl)-; AKOS026714293; 4-(Trifluoromethyl)-N-(4-chloro-3-nitrophenyl)benzothioamide
EINECS	Contact for details

Quality Control

Every batch of n-(4-Chloro-3-Nitrophenyl)-4-(Trifluoromethyl)Benzothioamide is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.