Description

4-Bromo-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for modern cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily used by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds to create biaryl structures, a common motif in drug discovery.
• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring halogenated, trifluoromethylated aromatic systems.
• Agrochemical Synthesis: Serves as a building block for novel herbicides, fungicides, and insecticides where the bromo- and trifluoromethyl- groups confer specific biological activity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Ligand and Catalyst Development: Used to synthesize novel ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects in fine chemical and CDMO (Contract Development and Manufacturing Organization) settings.

Basic Information

Product Name	4-Bromo-3-(Trifluoromethyl)Phenylboronic Acid Pinacol Ester
CAS No.	1256944-74-7
Molecular Formula	C₁₃H₁₅BBrF₃O₂
Molecular Weight	350.97 g/mol
Synonyms	4-Bromo-3-(trifluoromethyl)benzeneboronic acid pinacol ester; (4-Bromo-3-(trifluoromethyl)phenyl)boronic acid pinacol ester; 2-(4-Bromo-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Bromo-α,α,α-trifluoro-m-tolylboronic acid pinacol ester; Pinacol 4-Bromo-3-(trifluoromethyl)phenylboronate; B-(4-Bromo-3-(trifluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Standard quality parameters include purity assay (by HPLC/NMR), identity confirmation (IR, NMR), and control of key impurities. Certificates of Analysis (COA) are available upon request, providing full transparency for your R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.