Description

(3Ar*,6As*)-2-Methyltetrahydropyrrolo[3,4-C]Pyrrole-1,3(2H,3Ah)-Dione(Saltdata: Hcl) CAS NO 1256643-48-7 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and hydrochloride salt form. This compound is critical for research and development in medicinal chemistry, serving as a sophisticated building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing next-generation therapeutics, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its defined stereochemistry and pyrrolopyrrolidone core.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of proprietary compounds for client pipelines.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and bioactivity of complex nitrogen-containing heterocycles.

Basic Information

Product Name	(3Ar*,6As*)-2-Methyltetrahydropyrrolo[3,4-C]Pyrrole-1,3(2H,3Ah)-Dione(Saltdata: Hcl)
CAS No.	1256643-48-7
Molecular Formula	C8H11ClN2O2
Molecular Weight	202.64 g/mol
Synonyms	2-Methyltetrahydropyrrolo[3,4-c]pyrrole-1,3-dione hydrochloride; (3aR,6aS)-2-Methylhexahydropyrrolo[3,4-c]pyrrole-1,3-dione hydrochloride; 1,3(2H,3aH)-Pyrrolo[3,4-c]pyrroledione, hexahydro-2-methyl-, hydrochloride, (3aR,6aS)-rel-; 2-Methyl-1,3-dioxohexahydropyrrolo[3,4-c]pyrrole hydrochloride; (rel)-(3aR,6aS)-2-Methylhexahydropyrrolo[3,4-c]pyrrole-1,3-dione hydrochloride
EINECS	Contact for details

Quality Control

Our (3Ar*,6As*)-2-Methyltetrahydropyrrolo[3,4-C]Pyrrole-1,3(2H,3Ah)-Dione hydrochloride is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral methods for stereochemical confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.