Description

2,3-Difluoro-4-Methoxy-Dl-Phenylalanine is a fluorinated, methoxy-substituted derivative of the amino acid phenylalanine. This compound is a valuable non-natural amino acid building block, prized for its ability to impart unique electronic and steric properties to target molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide-based therapeutics, and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel drug candidates, particularly for metabolic and neurological disorders.
• Peptide Modification: Used to incorporate fluorine atoms into peptide chains, enhancing their metabolic stability, bioavailability, and binding affinity.
• Agrochemical Research: Serves as a building block for developing new herbicides and pesticides with improved efficacy and environmental profiles.
• Chemical Biology Probes: Employed in the design of labeled compounds and probes for studying enzyme mechanisms and protein interactions.
• Material Science: Potential precursor for specialty polymers and advanced materials requiring specific fluorinated aromatic components.

Basic Information

Product Name	2,3-Difluoro-4-Methoxy-Dl-Phenylalanine
CAS No.	1256482-63-9
Molecular Formula	C₁₀H₁₁F₂NO₃
Molecular Weight	231.20 g/mol
Synonyms	DL-2,3-Difluoro-4-methoxyphenylalanine; 4-Methoxy-2,3-difluoro-DL-phenylalanine; (RS)-2-Amino-3-(2,3-difluoro-4-methoxyphenyl)propanoic acid; 2,3-Difluoro-4-methoxy-DL-α-phenylalanine; 2,3-DF-4-OMe-DL-Phe; 2,3-Difluoro-4-methoxy-DL-homophenylalanine; (DL)-2,3-Difluoro-4-methoxyphenylalanine
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Methoxy-Dl-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.