Description

3-Fluoro-2-(Trifluoromethyl)-Dl-Phenylalanine, 97% is a high-purity, non-natural amino acid derivative characterized by its unique fluorinated side chain. This compound is a critical building block in modern pharmaceutical research and development, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and complex bioactive molecules. It is essential for medicinal chemists and process development scientists working in drug discovery, agrochemical research, and advanced material science, where precise molecular modification is required to modulate biological activity, metabolic stability, and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated peptide analogs and protease inhibitors.
• Drug Discovery & Medicinal Chemistry: Used to introduce fluorine atoms and trifluoromethyl groups into lead compounds to enhance potency, membrane permeability, and metabolic stability.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides and pesticides with improved efficacy and environmental profiles.
• Biochemical Research: Employed in the study of enzyme-substrate interactions and as a non-natural amino acid in peptide-based probes.
• Material Science: A potential monomer or modifier for creating specialty polymers with unique surface properties and chemical resistance.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of complex organic molecules.

Basic Information

Product Name	3-Fluoro-2-(Trifluoromethyl)-Dl-Phenylalanine, 97%
CAS No.	1256482-60-6
Molecular Formula	C₁₀H₉F₄NO₂
Molecular Weight	251.18 g/mol
Synonyms	DL-3-Fluoro-2-(trifluoromethyl)phenylalanine; (±)-3-Fluoro-2-(trifluoromethyl)phenylalanine; 2-(Trifluoromethyl)-3-fluorophenylalanine; 3-Fluoro-2-trifluoromethyl-DL-phenylalanine; Fmoc-3-Fluoro-2-(trifluoromethyl)-DL-phenylalanine (precursor); 3-Fluoro-α-methyl-2-(trifluoromethyl)benzenepropanoic acid (related); Amino acid derivative, fluorinated
EINECS	Contact for details

Quality Control

Every batch of 3-Fluoro-2-(Trifluoromethyl)-Dl-Phenylalanine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment supports compliance with the standards expected in pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.