Description

Lithium Triisopropyl 2-(5-Methylpyridyl)Borate is a specialized organoboron reagent, specifically a lithium borate salt, with the CAS number 1256364-31-4. This compound is valued for its role as a highly selective and reactive nucleophile in advanced organic synthesis, particularly in cross-coupling and functionalization reactions. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient methods for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing active pharmaceutical ingredients (APIs), especially in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific boronic ester functionalities.
• Materials Science: Employed in the development of organic electronic materials, such as OLEDs and organic semiconductors, where precise molecular structure is critical.
• Catalyst & Ligand Preparation: Serves as a precursor for generating novel boron-containing ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	Lithium Triisopropyl 2-(5-Methylpyridyl)Borate
CAS No.	1256364-31-4
Molecular Formula	C15H27BLiN
Molecular Weight	239.14 g/mol
Synonyms	Lithium 2-(5-Methylpyridyl)triisopropylborate; 2-(5-Methyl-2-pyridinyl)-1,1,1-tris(1-methylethyl)boron Lithium Salt; Triisopropyl(5-methylpyridin-2-yl)borate Lithium Salt; Lithium Triisopropyl(5-methyl-2-pyridyl)borate; (5-Methylpyridin-2-yl)triisopropylborate Lithium Complex; LiB(i-Pr)3(5-MePy); Lithium (5-Methyl-2-pyridyl)triisopropylborohydride (common misnomer)
EINECS	Contact for details

Quality Control

Our Lithium Triisopropyl 2-(5-Methylpyridyl)Borate is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C), HPLC for purity, and titration for active content, to ensure consistency and high performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry place at 2-8°C to maintain stability. Due to its hygroscopic and oxygen-sensitive nature, the container should only be opened in a controlled, moisture-free environment.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.