Description

2,5-Difluoro-1,4-Phenylenediboronic Acid is a high-purity, bifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex molecular architectures, particularly through Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require a reliable, high-quality reagent for synthesizing fluorinated organic compounds and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic rings to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used to create novel fluorinated herbicides, fungicides, and insecticides, leveraging the fluorine atom's ability to improve lipophilicity and target binding.
• Organic Light-Emitting Diodes (OLEDs): Serves as a monomer for constructing electron-transport or emissive layer materials in display and lighting technologies.
• Polymer & Material Science: Enables the synthesis of fluorinated polyarylenes, polyesters, and other high-performance polymers with enhanced thermal, chemical, and environmental resistance.
• Ligand & Catalyst Development: Utilized to prepare sophisticated boronate-based ligands for catalysis and molecular recognition applications.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on new coupling methodologies and fluorinated compound libraries.

Basic Information

Product Name	2,5-Difluoro-1,4-Phenylenediboronic Acid
CAS No.	1256358-83-4
Molecular Formula	C6H6B2F2O4
Molecular Weight	209.73 g/mol
Synonyms	1,4-Benzenediboronic acid, 2,5-difluoro-; 2,5-Difluorobenzene-1,4-diboronic acid; 2,5-Difluoro-p-phenylenediboronic acid; 2,5-Difluoro-1,4-benzenediboronic acid; 2,5-Difluoro-1,4-phenylenebis(boronic acid); 2,5-Difluoro-1,4-phenylene diboronate; 2,5-DFPDBA
EINECS	Contact for details

Quality Control

Our 2,5-Difluoro-1,4-Phenylenediboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant regulatory frameworks, including REACH and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect purity and reactivity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.