Description

3-Fluoro-4-(Thiophen-2-Ylmethoxymethyl)Phenylboronic Acid is a specialized organoboron building block designed for advanced synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated and thiophene motifs.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced properties.
• Materials Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs and OFETs.
• Ligand and Catalyst Development: Useful for synthesizing novel ligands and organometallic catalysts.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological systems.

Basic Information

Product Name	3-Fluoro-4-(Thiophen-2-Ylmethoxymethyl)Phenylboronic Acid
CAS No.	1256358-79-8
Molecular Formula	C12H12BFO3S
Molecular Weight	266.10 g/mol
Synonyms	[3-Fluoro-4-[(thiophen-2-ylmethoxy)methyl]phenyl]boronic acid; 2-Thiophenemethanol, α-[[2-fluoro-4-(dihydroxyboranyl)phenyl]methoxy]-; (3-Fluoro-4-((thiophen-2-ylmethoxy)methyl)phenyl)boronic acid; B-[3-Fluoro-4-[(2-thienylmethoxy)methyl]phenyl]boronic acid; 3-Fluoro-4-((thiophen-2-ylmethoxy)methyl)benzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-(Thiophen-2-Ylmethoxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical: 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.