Description

2-(4-Trifluoromethylphenoxy)Pyridine-5-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: Functions as a versatile boronic acid partner for forming carbon-carbon bonds, enabling the construction of biaryl and heterobiaryl structures prevalent in many functional molecules.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry teams exploring new synthetic routes and molecular libraries.
• Ligand Synthesis: Can be utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-(4-Trifluoromethylphenoxy)Pyridine-5-Boronic Acid
CAS No.	1256358-58-3
Molecular Formula	C12H9BF3NO3
Molecular Weight	283.01 g/mol
Synonyms	5-(4-(Trifluoromethyl)phenoxy)pyridine-2-boronic acid; [5-(4-Trifluoromethylphenoxy)-2-pyridyl]boronic acid; 2-(4-Trifluoromethylphenoxy)-5-pyridineboronic acid; 2-(α,α,α-Trifluoro-p-tolyloxy)pyridine-5-boronic acid; 2-(4-Trifluoromethylphenoxy)pyridin-5-ylboronic acid; 5-Borono-2-(4-(trifluoromethyl)phenoxy)pyridine; Pyridine, 5-borono-2-[4-(trifluoromethyl)phenoxy]-
EINECS	Contact for details

Quality Control

Our 2-(4-Trifluoromethylphenoxy)Pyridine-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.