Description

2-(4-Chlorophenylmethoxy)-5-Fluorophenylboronic Acid is a specialized organoboron compound, a key building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific fluorinated and chlorinated aromatic systems.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: A key reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	2-(4-Chlorophenylmethoxy)-5-Fluorophenylboronic Acid
CAS No.	1256358-54-9
Molecular Formula	C13H11BClFO3
Molecular Weight	279.49 g/mol
Synonyms	[2-[(4-Chlorophenyl)methoxy]-5-fluorophenyl]boronic Acid; 5-Fluoro-2-[(4-chlorobenzyl)oxy]benzeneboronic Acid; 2-[(4-Chlorobenzyl)oxy]-5-fluorobenzeneboronic Acid; (2-((4-Chlorobenzyl)oxy)-5-fluorophenyl)boronic Acid; Boronic acid, B-[2-[(4-chlorophenyl)methoxy]-5-fluorophenyl]-; 2-(4-Chlorobenzyloxy)-5-fluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenylmethoxy)-5-Fluorophenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and production needs with material suitable for research use and can provide material meeting GMP-grade standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.