Description

5-Fluoro-2-(3-Fluorophenylmethoxy)Phenylboronic Acid is a high-value, multi-fluorinated boronic acid derivative, a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting CNS disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the introduction of fluorine atoms enhances biological activity and environmental stability.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing biaryl and heterobiaryl structures prevalent in medicinal chemistry.
• Diagnostic Reagent Manufacturing: Potential use in synthesizing probes and ligands for diagnostic assays and imaging agents.

Basic Information

Product Name	5-Fluoro-2-(3-Fluorophenylmethoxy)Phenylboronic Acid
CAS No.	1256358-53-8
Molecular Formula	C₁₃H₁₁BF₂O₃
Molecular Weight	264.03 g/mol
Synonyms	[3-Fluoro-4-(3-fluorobenzyloxy)phenyl]boronic acid; 5-Fluoro-2-[(3-fluorophenyl)methoxy]benzeneboronic acid; (5-Fluoro-2-{[(3-fluorophenyl)methyl]oxy}phenyl)boronic acid; 2-(3-Fluorobenzyloxy)-5-fluorophenylboronic acid; 3-Fluoro-4-(3-fluorobenzyloxy)benzeneboronic acid; Boronic acid, B-[3-fluoro-4-[(3-fluorophenyl)methoxy]phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 5-Fluoro-2-(3-Fluorophenylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR (¹H, ¹³C, ¹⁹F, ¹¹B), and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay (Boronic Acid)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.