Description

5-Fluoro-2-(2-Fluorophenylmethoxy)Phenylboronic Acid is a high-purity, bifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, enabling efficient cross-coupling reactions for the construction of complex molecular architectures. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its boronic acid group for creating complex bioactive molecules.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLEDs and organic semiconductors, due to its conjugated structure.
• Chemical Biology Probes: Serves as a building block for creating bioconjugates and molecular probes used in diagnostic and imaging applications.
• Catalyst Ligand Development: Utilized in the preparation of specialized ligands for transition metal catalysis, enhancing reaction selectivity and efficiency.
• Academic & Contract Research: Essential for methodological development and scale-up studies in university and CRO laboratory settings.

Basic Information

Product Name	5-Fluoro-2-(2-Fluorophenylmethoxy)Phenylboronic Acid
CAS No.	1256358-52-7
Molecular Formula	C₁₃H₁₁BF₂O₃
Molecular Weight	264.04 g/mol
Synonyms	[2-(Benzyloxy)-5-fluorophenyl]boronic Acid; (5-Fluoro-2-((2-fluorobenzyl)oxy)phenyl)boronic Acid; 2-(2-Fluorobenzyloxy)-5-fluorophenylboronic Acid; 5-Fluoro-2-[(2-fluorophenyl)methoxy]benzeneboronic Acid; 2-[(2-Fluorobenzyl)oxy]-5-fluorobenzeneboronic Acid; B-[5-Fluoro-2-[(2-fluorophenyl)methoxy]phenyl]boronic Acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(2-Fluorophenylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.