Description

2-(4-Fluorophenylmethoxy)-5-Methylphenylboronic Acid is a specialized organoboron compound featuring a fluorinated aromatic ether moiety. This structural complexity makes it a valuable high-purity building block for advanced chemical synthesis, particularly in cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific fluorinated aromatic systems.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those for OLEDs.
• Ligand and Catalyst Development: Employed in the synthesis of sophisticated ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	2-(4-Fluorophenylmethoxy)-5-Methylphenylboronic Acid
CAS No.	1256358-49-2
Molecular Formula	C14H14BFO3
Molecular Weight	260.07 g/mol
Synonyms	[2-[(4-Fluorophenyl)methoxy]-5-methylphenyl]boronic acid; 5-Methyl-2-[(4-fluorobenzyl)oxy]phenylboronic acid; 2-[(4-Fluorobenzyl)oxy]-5-methylbenzeneboronic acid; (2-((4-Fluorobenzyl)oxy)-5-methylphenyl)boronic acid; Boronic acid, B-[2-[(4-fluorophenyl)methoxy]-5-methylphenyl]-; CAS 1256358-49-2
EINECS	Contact for details

Quality Control

Our production of 2-(4-Fluorophenylmethoxy)-5-Methylphenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications. Each lot is characterized by advanced analytical techniques including HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.