Description

5-Amino-2-Fluorophenylboronic Acid, Hcl is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. This compound matters for its role as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its fluorine and amino functional groups for bioactivity.
• Material Science Research: Serves as a building block for creating functionalized polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in the development of chemical probes and inhibitors for studying enzyme function and protein interactions.
• Diagnostic Reagent Development: Utilized in the synthesis of components for sensors and diagnostic assays due to its specific binding properties.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and catalysis research at universities and corporate R&D centers.

Basic Information

Product Name	5-Amino-2-Fluorophenylboronic Acid, Hcl
CAS No.	1256355-65-3
Molecular Formula	C6H8BClFNO2
Molecular Weight	191.40 g/mol
Synonyms	(5-Amino-2-fluorophenyl)boronic acid hydrochloride; 2-Fluoro-5-aminophenylboronic acid hydrochloride; 5-Amino-2-fluorobenzeneboronic acid HCl; B-(5-Amino-2-fluorophenyl)boronic acid hydrochloride; 2-Fluoro-5-aminobenzene-1-boronic acid hydrochloride; 5-Amino-2-fluorophenyl-Boronic Acid HCl; 1256355-65-3; 5-Amino-2-fluoro-benzeneboronic acid hydrochloride salt
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluorophenylboronic Acid, Hcl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.