Description

4-(2-Fluoroethoxy)Phenylboronic Acid is a specialized organoboron compound featuring a fluoroethoxy substituent, making it a valuable building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. This high-purity reagent is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluoroethoxy group can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-(2-Fluoroethoxy)Phenylboronic Acid
CAS No.	1256355-63-1
Molecular Formula	C8H10BFO3
Molecular Weight	183.98 g/mol
Synonyms	[4-(2-Fluoroethoxy)phenyl]boronic acid; 2-Fluoroethoxy-4-phenylboronic acid; 4-(2-Fluoroethoxy)benzeneboronic acid; (4-(2-Fluoroethoxy)phenyl)boronic acid; Boronic acid, B-[4-(2-fluoroethoxy)phenyl]-; 4-Fluoroethoxyphenylboronic Acid; p-(2-Fluoroethoxy)phenylboronic Acid
EINECS	Contact for details

Quality Control

Our 4-(2-Fluoroethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) for long-term storage to prevent decomposition. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.