Description

2-Methoxymethoxy-5-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound serving as a key synthetic intermediate. Its core value lies in enabling the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and advanced materials chemistry. This high-purity building block is essential for researchers and process chemists in pharmaceutical R&D, agrochemical development, and the synthesis of functional organic materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the boronic acid moiety facilitates the introduction of complex aromatic systems.
• Material Science: Enables the construction of novel organic frameworks, polymers, and liquid crystals for electronic and optoelectronic applications.
• Chemical Research: A versatile reagent in academic and industrial laboratories for methodology development and the synthesis of complex, polyfunctional molecules.
• Cross-Coupling Reactions: Primarily employed in palladium-catalyzed Suzuki-Miyaura couplings to create biaryl and heterobiaryl structures, which are prevalent in many functional molecules.

Basic Information

Product Name	2-Methoxymethoxy-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1256355-54-0
Molecular Formula	C10H12BF3O4
Molecular Weight	264.01 g/mol
Synonyms	[2-(Methoxymethoxy)-5-(trifluoromethyl)phenyl]boronic acid; 2-MOM-5-CF3-Phenylboronic Acid; (2-Methoxymethoxy-5-trifluoromethylphenyl)boronic Acid; 5-Trifluoromethyl-2-methoxymethoxyphenylboronic Acid; Boronic acid, B-[2-(methoxymethoxy)-5-(trifluoromethyl)phenyl]-; 2-MethoxyMethoxy-5-TrifluoroMethyl Benzeneboronic Acid
EINECS	Contact for details

Quality Control

Our production of 2-Methoxymethoxy-5-(Trifluoromethyl)Phenylboronic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.