Description

2-Benzyloxy-3-Fluorophenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing fluorinated biaryl motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection products, leveraging the fluorine atom for improved efficacy and environmental profile.
• Material Science: Building block for the development of organic electronic materials, such as ligands for OLEDs and other fluorinated polymers.
• Chemical Synthesis: Versatile reagent in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds under mild conditions.
• Ligand Synthesis: Intermediate for preparing sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Life Science Research: Tool compound for biochemical probing and the development of diagnostic agents and imaging probes.

Basic Information

Product Name	2-Benzyloxy-3-Fluorophenylboronic Acid
CAS No.	1256355-53-9
Molecular Formula	C₁₃H₁₂BFO₃
Molecular Weight	246.05 g/mol
Synonyms	(2-(Benzyloxy)-3-fluorophenyl)boronic Acid; 3-Fluoro-2-(phenylmethoxy)benzeneboronic Acid; 2-(Benzyloxy)-3-fluorobenzeneboronic Acid; B-[2-(Benzyloxy)-3-fluorophenyl]boronic Acid; 2-Benzyloxy-3-fluoroboronic Acid; 2-Benzyloxy-3-fluorophenylboronic Acid Pinacol Ester (precursor form); 2-(Benzyloxy)-3-fluoro-1-borabenzen
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.