Description

2-Methoxycarbonyl-3-Fluorophenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly for the formation of carbon-carbon bonds via Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating advanced functional polymers and electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing biaryl structures for oncology, CNS, and antiviral therapies.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Building block for synthesizing organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers.
• Chemical Biology & Diagnostics: Employed in the development of molecular probes, sensors, and bioconjugation reagents.
• Academic & R&D Laboratories: A versatile reagent for methodological development in cross-coupling chemistry and organoboron research.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring specific fluorinated boronic acid derivatives.

Basic Information

Product Name	2-Methoxycarbonyl-3-Fluorophenylboronic Acid
CAS No.	1256355-33-5
Molecular Formula	C9H8BFO4
Molecular Weight	197.97 g/mol
Synonyms	(2-Methoxycarbonyl-3-fluorophenyl)boronic acid; 3-Fluoro-2-(methoxycarbonyl)benzeneboronic acid; Methyl 3-fluoro-2-boronobenzoate; 2-Carbomethoxy-3-fluorobenzeneboronic acid; 3-Fluoro-2-methoxycarbonylphenylboronic acid; Methyl 2-borono-3-fluorobenzoate; 2-(Methoxycarbonyl)-3-fluorophenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxycarbonyl-3-Fluorophenylboronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.