Description

5-Fluoro-2-Formylphenylboronic Acid is a multifunctional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a formyl group and a boronic acid moiety on a fluorinated aromatic ring, makes it an exceptionally versatile reagent for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and as a precursor to various heterocycles.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing biaryl or heteroaryl motifs via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require fluorinated aromatic components.
• Material Science Research: Serves as a monomer or building block for the creation of advanced organic materials, such as organic semiconductors and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and sensors that leverage the specific binding properties of boronic acids to diols and other functional groups.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	5-Fluoro-2-Formylphenylboronic Acid
CAS No.	1256355-30-2
Molecular Formula	C7H6BFO3
Molecular Weight	167.93 g/mol
Synonyms	(5-Fluoro-2-formylphenyl)boronic acid; 2-Formyl-5-fluorophenylboronic acid; 5-Fluoro-2-carboxybenzene boronic acid (tautomer); 5-Fluoro-2-formylbenzeneboronic acid; 2-Borono-5-fluorobenzaldehyde; 5-Fluoro-2-aldehyde phenylboronic acid; 5-Fluoro-2-formylphenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.