Description

3-(Benzyloxy)-5-Bromophenylboronic Acid is a specialized organoboron compound that serves as a versatile building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables key cross-coupling reactions, and the bromo and benzyloxy substituents provide handles for further structural elaboration. This high-purity intermediate is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used in the development of organic electronic materials, such as polymers for OLEDs and semiconductors.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	3-(Benzyloxy)-5-Bromophenylboronic Acid
CAS No.	1256355-21-1
Molecular Formula	C13H12BBrO3
Molecular Weight	307.95 g/mol
Synonyms	(3-(Benzyloxy)-5-bromophenyl)boronic acid; 5-Bromo-3-(phenylmethoxy)benzeneboronic acid; 3-Benzyloxy-5-bromobenzeneboronic acid; B-(3-(Benzyloxy)-5-bromophenyl)boronic acid; [3-(Benzyloxy)-5-bromophenyl]boronic acid
EINECS	Contact for details

Quality Control

Our 3-(Benzyloxy)-5-Bromophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.