Description

5-Iodo-2-Trifluoromethoxyphenylboronic Acid is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its unique structure, featuring both an iodine substituent and a trifluoromethoxy group on the boronic acid scaffold, makes it a critical reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging the stability imparted by the trifluoromethoxy group.
• Ligand & Catalyst Development: Serves as a building block for synthesizing specialized ligands and catalysts used in asymmetric synthesis and material science.
• Functional Material Research: Incorporated into the backbone of organic electronic materials, such as OLEDs and OFETs, to modify electronic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	5-Iodo-2-Trifluoromethoxyphenylboronic Acid
CAS No.	1256355-12-0
Molecular Formula	C7H5BF3IO3
Molecular Weight	315.83 g/mol
Synonyms	(5-Iodo-2-(trifluoromethoxy)phenyl)boronic acid; 2-Trifluoromethoxy-5-iodophenylboronic acid; Boronic acid, B-[5-iodo-2-(trifluoromethoxy)phenyl]-; 5-Iodo-2-(trifluoromethoxy)benzeneboronic acid; 1256355-12-0; 5-Iodo-2-trifluoromethoxybenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-Trifluoromethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.