Description

2-Fluoro-3-Hydroxymethylphenylboronic Acid is a specialized organoboron compound that serves as a crucial building block in modern synthetic chemistry. Its value lies in its dual functional groups, which enable precise cross-coupling reactions for constructing complex molecular architectures. This high-purity intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated biaryl compounds with potential therapeutic activity.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and material science.
• OLED Material Development: Employed in the synthesis of fluorinated organic semiconductors and electron-transport materials for display technologies.
• Chemical Biology Probes: Facilitates the creation of tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis: Provides a versatile handle for contract research organizations (CROs) and fine chemical manufacturers to build bespoke compounds for client projects.

Basic Information

Item	Details
Product Name	2-Fluoro-3-Hydroxymethylphenylboronic Acid
CAS No.	1256355-08-4
Molecular Formula	C7H8BFO3
Molecular Weight	169.95 g/mol
Synonyms	(2-Fluoro-3-(hydroxymethyl)phenyl)boronic acid; 3-Borono-2-fluorobenzyl alcohol; 2-Fluoro-3-(hydroxymethyl)benzeneboronic acid; 2-Fluoro-3-hydroxymethylbenzeneboronic acid; (3-(Hydroxymethyl)-2-fluorophenyl)boronic acid; B-(2-Fluoro-3-(hydroxymethyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3-Hydroxymethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.