Description

4-Chloro-2-(2-Methoxyethoxy)Phenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides that require specific chlorinated phenylboronic acid derivatives.
• Material Science Research: Building block for the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects requiring high-fidelity coupling reactions.

Basic Information

Product Name	4-Chloro-2-(2-Methoxyethoxy)Phenylboronic Acid
CAS No.	1256354-97-8
Molecular Formula	C9H12BClO4
Molecular Weight	230.45 g/mol
Synonyms	[4-Chloro-2-(2-methoxyethoxy)phenyl]boronic acid; 2-(2-Methoxyethoxy)-4-chlorophenylboronic acid; 4-Chloro-2-(2-methoxyethoxy)benzeneboronic acid; (4-Chloro-2-(2-methoxyethoxy)phenyl)boronic acid; Boronic acid, B-[4-chloro-2-(2-methoxyethoxy)phenyl]-; CAS 1256354-97-8
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(2-Methoxyethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (argon or nitrogen) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.