Description

2,4-Dichloro-5-(Trifluoromethoxy)Phenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging the trifluoromethoxy group for enhanced biological activity and stability.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands and organometallic catalysts for asymmetric synthesis and other advanced catalytic processes.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to develop molecular probes and sensors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs serving the global fine chemical market.

Basic Information

Product Name	2,4-Dichloro-5-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	1256354-96-7
Molecular Formula	C7H4BCl2F3O3
Molecular Weight	278.82 g/mol
Synonyms	[2,4-Dichloro-5-(trifluoromethoxy)phenyl]boronic acid; (2,4-Dichloro-5-(trifluoromethoxy)phenyl)boronic acid; Boronic acid, B-[2,4-dichloro-5-(trifluoromethoxy)phenyl]-; 2,4-Dichloro-5-(trifluoromethoxy)benzeneboronic acid; 2,4-Dichloro-alpha,alpha,α-trifluoro-m-anisate boronic acid; 5-Trifluoromethoxy-2,4-dichlorophenylboronic acid
EINECS	Contact for details

Quality Control

Our production of 2,4-Dichloro-5-(Trifluoromethoxy)Phenylboronic Acid adheres to stringent quality management protocols. Every batch is characterized and tested using advanced analytical techniques (including NMR, HPLC, and LC-MS) to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.