Description

2-Fluoro-5-Isopropylphenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing fluorinated biphenyl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the isopropyl and fluorine substituents for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling reactions.
• Ligand Synthesis: Can be utilized to create novel bidentate or polydentate ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Fluoro-5-Isopropylphenylboronic Acid
CAS No.	1256354-92-3
Molecular Formula	C9H12BFO2
Molecular Weight	181.99 g/mol
Synonyms	(2-Fluoro-5-isopropylphenyl)boronic acid; 2-Fluoro-5-(propan-2-yl)phenylboronic acid; 5-Isopropyl-2-fluorophenylboronic acid; Boronic acid, B-[2-fluoro-5-(1-methylethyl)phenyl]-; 2-Fluoro-5-isopropylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Isopropylphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.