Description

(3-(Difluoromethyl)Phenyl)Methanamine Hydrochloride is a high-purity, synthetically valuable organic intermediate. This compound is crucial for its role as a versatile building block in advanced pharmaceutical and agrochemical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for constructing novel molecular entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides, leveraging the difluoromethyl group for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and functional polymers, where the aromatic amine moiety is essential.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	(3-(Difluoromethyl)Phenyl)Methanamine Hydrochloride
CAS No.	1256353-07-7
Molecular Formula	C8H10ClF2N
Molecular Weight	193.62 g/mol
Synonyms	1-[3-(Difluoromethyl)phenyl]methanamine hydrochloride; 3-(Difluoromethyl)benzylamine hydrochloride; (3-(Difluoromethyl)benzyl)amine hydrochloride; α-(3-Difluoromethylphenyl)methylamine hydrochloride; Benzenemethanamine, 3-(difluoromethyl)-, hydrochloride; [3-(Difluoromethyl)phenyl]methanamine HCl; 3-Difluoromethylbenzylamine HCl
EINECS	Contact for details

Quality Control

Our (3-(Difluoromethyl)Phenyl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.