Description

3-Benzyloxy-4-Chloro-2-Fluorophenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, especially those containing biaryl structures.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Material Science: Building block for creating advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Research: Essential reagent in academic and industrial R&D for constructing fluorinated and chlorinated aromatic systems.
• Ligand and Catalyst Development: Used to synthesize novel ligands for transition metal catalysis.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	3-Benzyloxy-4-Chloro-2-Fluorophenylboronic Acid
CAS No.	1256346-27-6
Molecular Formula	C13H11BClFO3
Molecular Weight	279.49 g/mol
Synonyms	4-Chloro-2-fluoro-3-(phenylmethoxy)benzeneboronic acid; (3-(Benzyloxy)-4-chloro-2-fluorophenyl)boronic acid; 3-Benzyloxy-4-chloro-2-fluorobenzeneboronic acid; B-(3-Benzyloxy-4-chloro-2-fluorophenyl)boronic acid; 1256346-27-6; 3-(Benzyloxy)-4-chloro-2-fluorophenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Benzyloxy-4-Chloro-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.