Description

2-(Methylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid CAS NO 1256346-08-3 is a high-value, multi-functional boronic acid derivative crucial for modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require a reliable, high-purity building block for developing novel active ingredients.

Application

This versatile boronic acid is a key intermediate in the synthesis of advanced chemical entities. Its primary applications include:

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyridine and trifluoromethyl motifs.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in organic light-emitting diodes (OLEDs), liquid crystals, and other advanced materials.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-(Methylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid
CAS No.	1256346-08-3
Molecular Formula	C8H7BF3NO2S
Molecular Weight	249.02 g/mol
Synonyms	2-(Methylthio)-5-(trifluoromethyl)pyridine-3-boronic acid; 3-Borono-2-(methylthio)-5-(trifluoromethyl)pyridine; [2-(Methylsulfanyl)-5-(trifluoromethyl)pyridin-3-yl]boronic acid; 2-Methylsulfanyl-5-trifluoromethylpyridine-3-boronic acid; 5-Trifluoromethyl-2-methylthiopyridine-3-boronic acid; Boronic acid, B-[2-(methylthio)-5-(trifluoromethyl)-3-pyridinyl]-; CAS 1256346-08-3
EINECS	Contact for details

Quality Control

Our 2-(Methylthio)-5-(Trifluoromethyl)Pyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.