Description

2-Butoxy-5-(Trifluoromethyl)Phenylboronic Acid is a high-purity, synthetically valuable organoboron compound. This chemical serves as a crucial building block in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the trifluoromethylphenyl moiety, which is prized for its metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides, where the boronic acid group enables efficient construction of complex biaryl structures.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, via polymerization or small-molecule synthesis.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Chemical Biology Probes: Useful in constructing molecular probes and tags for studying biological processes, leveraging the specificity of boronic acids for diol recognition.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific aryl boronic acid derivatives.

Basic Information

Product Name	2-Butoxy-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1256345-98-8
Molecular Formula	C11H14BF3O3
Molecular Weight	262.04 g/mol
Synonyms	[2-Butoxy-5-(trifluoromethyl)phenyl]boronic acid; (2-Butoxy-5-(trifluoromethyl)phenyl)boronic acid; 2-Butoxy-5-(trifluoromethyl)benzeneboronic acid; 2-n-Butoxy-5-trifluoromethylphenylboronic Acid; Boronic acid, B-[2-butoxy-5-(trifluoromethyl)phenyl]-; 1256345-98-8; 2-Butoxy-alpha,alpha,α-trifluoro-p-tolylboronic acid
EINECS	Contact for details

Quality Control

Our 2-Butoxy-5-(Trifluoromethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.