Description

3-Butoxy-5-(Trifluoromethoxy)Phenylboronic Acid is a specialized organoboron compound designed for advanced synthetic chemistry applications. This boronic acid derivative is a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethoxy-substituted aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Used in the synthesis of organic electronic materials, such as those for OLEDs and semiconductors.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological processes and target engagement.

Basic Information

Product Name	3-Butoxy-5-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	1256345-96-6
Molecular Formula	C11H14BF3O4
Molecular Weight	278.04 g/mol
Synonyms	[3-(Butoxy)-5-(trifluoromethoxy)phenyl]boronic acid; 3-Butoxy-5-(trifluoromethoxy)benzeneboronic acid; (3-Butoxy-5-(trifluoromethoxy)phenyl)boronic acid; Boronic acid, B-[3-(butoxy)-5-(trifluoromethoxy)phenyl]-; 1256345-96-6
EINECS	Contact for details

Quality Control

Our 3-Butoxy-5-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot is analyzed using advanced techniques including NMR and HPLC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive. For long-term storage, consider storing under an inert gas such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥95.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.