Description

3-(Benzyloxy)-5-(Trifluoromethoxy)Phenylboronic Acid is a high-purity, synthetically valuable boronic acid derivative. This compound serves as a critical building block in modern organic synthesis, particularly in cross-coupling reactions to form new carbon-carbon bonds. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, where its unique trifluoromethoxy and benzyloxy substituents enable the introduction of specific functional groups and enhanced properties into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Employed in the synthesis of advanced organic materials, such as polymers and liquid crystals, for electronic and optical applications.
• Chemical Synthesis: Functions as a versatile reagent for introducing the (benzyloxy)-trifluoromethoxyphenyl moiety into more complex organic molecules.
• Academic & R&D: A valuable tool for methodological development in synthetic organic chemistry laboratories worldwide.

Basic Information

Item	Details
Product Name	3-(Benzyloxy)-5-(Trifluoromethoxy)Phenylboronic Acid
CAS No.	1256345-95-5
Molecular Formula	C14H12BF3O4
Molecular Weight	312.05 g/mol
Synonyms	[3-(Benzyloxy)-5-(trifluoromethoxy)phenyl]boronic acid; 3-Benzyloxy-5-trifluoromethoxyphenylboronic acid; (3-(Benzyloxy)-5-(trifluoromethoxy)phenyl)boronic acid; Boronic acid, B-[3-(phenylmethoxy)-5-(trifluoromethoxy)phenyl]-; 1256345-95-5; 3-BnO-5-TFMPhenyl-B(OH)2
EINECS	Contact for details

Quality Control

Every batch of 3-(Benzyloxy)-5-(Trifluoromethoxy)Phenylboronic Acid is manufactured under strict quality management protocols. We ensure high purity and batch-to-batch consistency through comprehensive analytical testing, including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.