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7-Fluorobenzo[D][1,3]Dioxol-4-Ylboronic Acid CAS NO 1256345-92-2


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CAS No.:1256345-92-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-Fluorobenzo[D][1,3]Dioxol-4-Ylboronic Acid is a high-purity, multifunctional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing the benzodioxole scaffold.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring fluorinated aromatic structures.
  • Material Science: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials through palladium-catalyzed coupling reactions.
  • Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries for screening.
  • Ligand Synthesis: Intermediate for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name 7-Fluorobenzo[D][1,3]Dioxol-4-Ylboronic Acid
CAS No. 1256345-92-2
Molecular Formula C7H6BFO4
Molecular Weight 183.93 g/mol
Synonyms 4-Borono-7-fluoro-1,3-benzodioxole; 7-Fluoro-1,3-benzodioxole-4-boronic acid; (7-Fluoro-1,3-benzodioxol-4-yl)boronic acid; 7-Fluoro-1,3-benzodioxol-4-ylboronic acid; 7-Fluoro-benzo[1,3]dioxol-4-yl-boronic acid; 7-F-BDBA; F-BDBA Boronic Acid
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Quality Control

Every batch of 7-Fluorobenzo[D][1,3]Dioxol-4-Ylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive coupling reactions. A detailed Certificate of Analysis (COA) including results for assay, purity (HPLC), and identity confirmation is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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