Description

2-Chloro-3-Ethoxyphenylboronic Acid is a high-purity organoboron building block, essential for modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, enabling the introduction of specific chlorinated ethoxyphenyl motifs.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and organic electronic materials through cross-coupling polymerization.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and target engagement.
• Catalyst Ligand Synthesis: Used to prepare specialized ligands for transition metal catalysts, enhancing selectivity and efficiency in catalytic processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-3-Ethoxyphenylboronic Acid
CAS No.	1256345-57-9
Molecular Formula	C8H10BClO3
Molecular Weight	200.43 g/mol
Synonyms	(2-Chloro-3-ethoxyphenyl)boronic acid; 2-Chloro-3-ethoxybenzeneboronic acid; Boronic acid, B-(2-chloro-3-ethoxyphenyl)-; 2-Chloro-3-ethoxy phenyl boronic acid; 2-Cl-3-EtO-PhB(OH)2; CAS 1256345-57-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Ethoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and consistent performance in coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.