Description

5-(1-Cyanocyclopropyl)-2-Fluorophenylboronic Acid is a high-value, multi-functional boronic acid derivative used as a critical building block in advanced organic synthesis. Its unique structure, featuring both a cyano-substituted cyclopropyl ring and a fluorine atom, makes it an essential reagent for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the fluorine and boronic acid functionalities for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and the development of chemical tools for biological target identification.
• Catalyst Ligand Synthesis: The boronic acid group can be utilized to create sophisticated ligands for transition metal catalysis.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic pathways in academic and CRO laboratories.

Basic Information

Product Name	5-(1-Cyanocyclopropyl)-2-Fluorophenylboronic Acid
CAS No.	1256345-50-2
Molecular Formula	C10H9BFNO2
Molecular Weight	205.00 g/mol
Synonyms	[5-(1-Cyanocyclopropyl)-2-fluorophenyl]boronic acid; 2-Fluoro-5-(1-cyanocyclopropyl)benzeneboronic acid; (5-(1-Cyanocyclopropyl)-2-fluorophenyl)boronic Acid; Boronic acid, B-[5-(1-cyanocyclopropyl)-2-fluorophenyl]-; 5-(1-Cyano-cyclopropyl)-2-fluoro-phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 5-(1-Cyanocyclopropyl)-2-Fluorophenylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.