Description

3-n-Propoxy-5-(Trifluoromethyl)Phenylboronic Acid is a specialized organoboron compound, a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This high-purity boronic acid is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing trifluoromethyl groups for enhanced metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the propoxy and trifluoromethyl motifs can contribute to biological activity and environmental profile.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors.
• Ligand and Catalyst Development: Employed in the synthesis of complex ligands for catalysis and in the preparation of boron-containing molecular frameworks for sensor applications.
• Chemical Biology Probes: Useful in the design and synthesis of probes and inhibitors for studying biological pathways and enzyme functions.

Basic Information

Product Name	3-n-Propoxy-5-(Trifluoromethyl)Phenylboronic Acid
CAS No.	1256345-47-7
Molecular Formula	C10H12BF3O3
Molecular Weight	248.01 g/mol
Synonyms	[3-(Propoxy)-5-(trifluoromethyl)phenyl]boronic acid; 3-Propoxy-5-(trifluoromethyl)benzeneboronic acid; (3-Propoxy-5-(trifluoromethyl)phenyl)boronic acid; Boronic acid, B-[3-(propoxy)-5-(trifluoromethyl)phenyl]-; 3-n-Propoxy-α,α,α-trifluoro-m-tolylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-n-Propoxy-5-(Trifluoromethyl)Phenylboronic Acid is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results for purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent oxidation and hydrolysis. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.