Description

3-Butoxy-5-Trifluoromethylphenylboronic Acid is a specialized organoboron compound, specifically a boronic acid derivative, designed for advanced synthetic chemistry. This compound is a critical building block in modern organic synthesis, valued for its ability to participate in key cross-coupling reactions to form complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the boronic acid moiety enables efficient construction of complex heterocyclic systems.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and semiconductors, due to its aromatic and functionalized structure.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and sensors that leverage boronic acid's affinity for diols, useful in carbohydrate sensing and labeling applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale API (Active Pharmaceutical Ingredient) development projects.

Basic Information

Product Name	3-Butoxy-5-Trifluoromethylphenylboronic Acid
CAS No.	1256345-45-5
Molecular Formula	C11H14BF3O3
Molecular Weight	262.04 g/mol
Synonyms	(3-Butoxy-5-(trifluoromethyl)phenyl)boronic acid; 3-Butoxy-5-(trifluoromethyl)benzeneboronic acid; B-[3-Butoxy-5-(trifluoromethyl)phenyl]boronic acid; (3-n-Butoxy-5-trifluoromethylphenyl)boronic acid; Boronic acid, B-[3-butoxy-5-(trifluoromethyl)phenyl]-; 5-Trifluoromethyl-3-butoxyphenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-Butoxy-5-Trifluoromethylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >95% by HPLC), and impurity profiles is provided with every shipment to guarantee traceability and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.