Description

(S)-2-((Methoxycarbonyl)Amino)-3-Methylbutanoic Acid is a high-purity chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing peptide-based therapeutics and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel peptide drugs and protease inhibitors.
• API Development: Used as a building block for constructing active pharmaceutical ingredients requiring specific stereochemistry.
• Bioconjugation: Serves as a linker or spacer molecule in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Chemical Biology Research: Employed in the study of enzyme mechanisms and as a substrate analog in biochemical assays.
• Asymmetric Synthesis: Acts as a starting material or auxiliary in catalytic asymmetric reactions to introduce chiral centers.
• Peptidomimetics: Integral for designing and synthesizing peptidomimetic compounds with enhanced metabolic stability.

Basic Information

Product Name	(S)-2-((Methoxycarbonyl)Amino)-3-Methylbutanoic Acid
CAS No.	1255936-24-3
Molecular Formula	C8H15NO4
Molecular Weight	189.21 g/mol
Synonyms	L-Valine, N-[(methoxycarbonyl)]-; N-Carbomethoxy-L-valine; (S)-2-(Methoxycarbonylamino)-3-methylbutanoic acid; N-Methoxycarbonyl-L-valine; L-N-Methoxycarbonylvaline; (2S)-2-[(Methoxycarbonyl)amino]-3-methylbutanoic acid; Methyl N-L-valylcarbamate
EINECS	Contact for details

Quality Control

Our (S)-2-((Methoxycarbonyl)Amino)-3-Methylbutanoic Acid is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, chiral purity, and residual solvent analysis. Certificates of Analysis (COA) documenting compliance with agreed specifications are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.