Description

(3-Fluoro-4-(3-Fluoropropoxy)Phenyl)Boronic Acid is a specialized boronic acid derivative featuring both a fluorine substituent and a fluoropropoxy side chain, making it a valuable building block for modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for creating fluorinated drug candidates, particularly in oncology, CNS, and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and affinity ligands that target specific enzymes or proteins.
• Catalyst & Ligand Development: Acts as a precursor for creating novel palladium catalysts or bidentate ligands used in asymmetric synthesis.
• Academic & Contract Research: A critical reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	(3-Fluoro-4-(3-Fluoropropoxy)Phenyl)Boronic Acid
CAS No.	1254118-57-4
Molecular Formula	C9H11BF2O3
Molecular Weight	216.00 g/mol
Synonyms	[3-Fluoro-4-(3-fluoropropoxy)phenyl]boronic acid; 3-Fluoro-4-(3-fluoropropoxy)benzeneboronic acid; (3-Fluoro-4-(3-fluoropropoxy)phenyl)boronic acid; Boronic acid, B-[3-fluoro-4-(3-fluoropropoxy)phenyl]-; 4-(3-Fluoropropoxy)-3-fluorophenylboronic acid; 3-Fluoro-4-(3-fluoropropoxy)phenylboronic acid; CAS 1254118-57-4
EINECS	Contact for details

Quality Control

Our (3-Fluoro-4-(3-Fluoropropoxy)Phenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.