Description

(3-(Difluoromethyl)-4-Fluorophenyl)Boronic Acid is a high-purity, synthetically valuable organoboron compound. It serves as a critical building block in modern cross-coupling reactions, enabling the efficient construction of complex fluorinated aromatic structures. This material is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated drug candidates, including kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used to create advanced fluorinated active ingredients for crop protection products, leveraging the unique properties of fluorine to enhance efficacy and environmental stability.
• Material Science Research: Employed in the development of novel fluorinated organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of fluorinated probes for imaging and diagnostic applications.
• Catalyst Ligand Development: Serves as a starting material for synthesizing specialized boronate-based ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(3-(Difluoromethyl)-4-Fluorophenyl)Boronic Acid
CAS No.	1254118-35-8
Molecular Formula	C7H6BF3O2
Molecular Weight	189.93 g/mol
Synonyms	[3-(Difluoromethyl)-4-fluorophenyl]boronic acid; 4-Fluoro-3-(difluoromethyl)benzeneboronic acid; (3-(Difluoromethyl)-4-fluorophenyl)boronic acid; Boronic acid, B-[3-(difluoromethyl)-4-fluorophenyl]-; 3-(Difluoromethyl)-4-fluorobenzeneboronic acid; 4-Fluoro-3-difluoromethylphenylboronic acid
EINECS	Contact for details

Quality Control

Our (3-(Difluoromethyl)-4-Fluorophenyl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.