Description

tert-Butyl (4-Amino-1-Methylcyclohexyl)Carbamate is a high-purity, protected amine derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily utilized by medicinal chemists and process development scientists in the life sciences industry for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, especially those targeting the central nervous system (CNS) or other therapeutic areas.
• Peptidomimetic Chemistry: Serves as a protected cyclohexylamine moiety for the construction of peptide analogs and conformationally constrained scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to introduce specific steric and electronic properties.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for clinical trial material production.
• Custom Synthesis Building Block: Supplied to contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl (4-Amino-1-Methylcyclohexyl)Carbamate
CAS No.	1254058-26-8
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Methyl-4-[(tert-butoxycarbonyl)amino]cyclohexanamine; 4-Amino-1-methylcyclohexyl carbamic acid tert-butyl ester; tert-Butyl N-(4-amino-1-methylcyclohexyl)carbamate; Boc-4-amino-1-methylcyclohexylamine; (4-Amino-1-methyl-cyclohexyl)-carbamic acid tert-butyl ester; 1-Methyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]cyclohexan-1-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Amino-1-Methylcyclohexyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.