Description

2-Bromo-5-Iodobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique bifunctional halogen substitution pattern makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as cross-coupling reactions and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagging reagent due to its reactive halogen sites.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a building block for electron-transport materials and emissive layer components.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	2-Bromo-5-Iodobenzonitrile
CAS No.	1252046-13-1
Molecular Formula	C7H3BrIN
Molecular Weight	307.92 g/mol
Synonyms	5-Iodo-2-bromobenzonitrile; 2-Bromo-5-iodobenzene carbonitrile; Benzonitrile, 2-bromo-5-iodo-; 2-Bromo-5-iodo-benzonitrile; 2-Bromo-5-iodobenzonitrile (CAS 1252046-13-1); 2-Br-5-I-C6H3-CN
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Iodobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.