Description

Cyclobutanepropanoic Acid, α-Amino-, Methyl Ester, (αr)- is a high-purity chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. Its unique cyclobutane-propanoic acid ester structure makes it a valuable precursor for constructing complex molecular architectures with defined stereochemistry. This compound is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for constructing constrained peptide mimetics and bioactive molecules.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the cyclobutane ring system can impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The α-amino acid ester moiety is integral for synthesizing conformationally restricted peptide analogs in medicinal chemistry.
• Material Science Precursor: Potential use in synthesizing specialized monomers for advanced polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Cyclobutanepropanoic Acid, α-Amino-, Methyl Ester, (αr)-
CAS No.	1251904-02-5
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(R)-Methyl 3-amino-3-cyclobutylpropanoate; (αR)-α-Aminocyclobutanepropanoic Acid Methyl Ester; Methyl (R)-3-amino-3-cyclobutylpropanoate; 3-Cyclobutyl-β-alanine Methyl Ester (stereospecific); (R)-3-Amino-3-cyclobutylpropionic Acid Methyl Ester; (R)-Methyl 3-cyclobutyl-3-aminopropanoate; (R)-3-Cyclobutyl-3-aminopropanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Cyclobutanepropanoic Acid, α-Amino-, Methyl Ester, (αr)- adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity verification. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.