Description

3-(2-Methoxyphenyl)But-2-Enenitrile is a specialized organic nitrile building block featuring a methoxyphenyl substituent. This compound is valued for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients and fine chemicals. The compound, with CAS number 1251474-62-0, is supplied to meet the stringent requirements of advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its nitrile functionality.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Intermediate for the production of advanced polymers and liquid crystals with specific optical properties.
• Chemical Biology: Used in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & Industrial R&D: Fundamental research chemical for exploring new organic reactions and synthetic methodologies.

Basic Information

Product Name	3-(2-Methoxyphenyl)But-2-Enenitrile
CAS No.	1251474-62-0
Molecular Formula	C11H11NO
Molecular Weight	173.21 g/mol
Synonyms	2-Methoxy-β-methylcinnamonitrile; (E)-3-(2-Methoxyphenyl)-2-butenenitrile; 3-(2-Methoxyphenyl)but-2-enenitrile; (E)-3-(o-Methoxyphenyl)crotononitrile; 2-Butenenitrile, 3-(2-methoxyphenyl)-; o-Methoxy-β-methylcinnamonitrile; β-Methyl-2-methoxycinnamonitrile
EINECS	Contact for details

Quality Control

Our 3-(2-Methoxyphenyl)But-2-Enenitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.