Description

8-(Trifluoromethoxy)Quinoline is a high-value, fluorinated heterocyclic building block of significant interest in advanced chemical synthesis. Its core value lies in the unique combination of the quinoline scaffold and the trifluoromethoxy group, which is prized for modulating the physicochemical properties of target molecules. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing functional organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Employed in the design of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Development: The quinoline nitrogen can act as a coordinating site in metal-organic complexes for catalytic applications.
• Custom Synthesis & Scale-Up: Available for contract research organizations (CROs) and chemical companies requiring custom fluorinated building blocks for proprietary projects.

Basic Information

Product Name	8-(Trifluoromethoxy)Quinoline
CAS No.	1251032-62-8
Molecular Formula	C₁₀H₆F₃NO
Molecular Weight	213.16 g/mol
Synonyms	Quinoline, 8-(trifluoromethoxy)-; 8-Trifluoromethoxyquinoline; 8-(Trifluoromethoxy)quinoline; 1251032-62-8; 8-OCF3-Quinoline; 8-(Trifluorométhoxy)quinoléine; 8-(Trifluormethoxy)chinolin
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethoxy)Quinoline is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP standards where applicable to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.